Shkenc\u00ebtar\u00ebt kan\u00eb arritur t\u00eb zgjidhin nj\u00eb mister q\u00eb kishte mbetur i pazbardhur p\u00ebr m\u00eb shum\u00eb se gjysm\u00eb shekulli, duke identifikuar nj\u00eb sistem t\u00eb ri t\u00eb grupeve t\u00eb gjakut. Gjith\u00e7ka nisi nga nj\u00eb most\u00ebr gjaku e marr\u00eb n\u00eb vitin 1972 nga nj\u00eb grua shtatz\u00ebn\u00eb, n\u00eb t\u00eb cil\u00ebn mungonte nj\u00eb molekul\u00eb e pazakont\u00eb n\u00eb sip\u00ebrfaqen e qelizave t\u00eb kuqe t\u00eb gjakut.<\/p>\n
Zbulimi, i publikuar n\u00eb vitin 2024 nga studiues nga Britania e Madhe dhe Izraeli, p\u00ebrb\u00ebn nj\u00eb hap t\u00eb r\u00ebnd\u00ebsish\u00ebm n\u00eb kuptimin e formave t\u00eb rralla t\u00eb gjakut dhe rreziqeve q\u00eb ato paraqesin gjat\u00eb transfuzioneve.<\/p>\n
M\u00eb shum\u00eb se ABO dhe Rh<\/strong><\/p>\n Shumica e njer\u00ebzve njohin vet\u00ebm grupet e gjakut ABO dhe faktorin Rh, por n\u00eb realitet ekzistojn\u00eb dhjet\u00ebra sisteme t\u00eb tjera t\u00eb bazuara n\u00eb proteina dhe sheqerna t\u00eb ndrysh\u00ebm q\u00eb ndodhen n\u00eb sip\u00ebrfaqen e qelizave t\u00eb kuqe t\u00eb gjakut. K\u00ebto struktura, t\u00eb quajtura antigjene, i lejojn\u00eb organizmit t\u00eb dalloj\u00eb qelizat e veta nga ato t\u00eb huaja. Rruga drejt zbulimit<\/strong><\/p>\n T\u00eb dh\u00ebnat tregojn\u00eb se mbi 99.9 p\u00ebr qind e njer\u00ebzve mbartin nj\u00eb antigjen t\u00eb quajtur AnWj<\/strong>. Ky antigjen mungonte n\u00eb mostr\u00ebn e vitit 1972, duke e b\u00ebr\u00eb rastin jasht\u00ebzakonisht t\u00eb rrall\u00eb. Studiuesit zbuluan se AnWj lidhet me nj\u00eb protein\u00eb t\u00eb ve\u00e7ant\u00eb, t\u00eb quajtur MAL<\/strong>, dhe p\u00ebr k\u00ebt\u00eb arsye sistemi i ri i grupeve t\u00eb gjakut u em\u00ebrtua pik\u00ebrisht \u201cMAL\u201d.<\/p>\n Ata identifikuan gjithashtu pacient\u00eb q\u00eb ishin AnWj-negativ\u00eb edhe pa mutacionin tipik gjenetik, gj\u00eb q\u00eb sugjeron se disa s\u00ebmundje apo \u00e7rregullime t\u00eb tjera sh\u00ebndet\u00ebsore mund t\u00eb pengojn\u00eb prodhimin e k\u00ebtij antigjeni.<\/p>\n Gjeni q\u00eb zgjidhi misterin<\/strong><\/p>\n P\u00ebr t\u00eb konfirmuar shkakun, shkenc\u00ebtar\u00ebt fut\u00ebn gjenin normal MAL<\/strong> n\u00eb qeliza q\u00eb nuk e shfaqnin antigjenin AnWj. Pas k\u00ebtij veprimi, antigjeni u shfaq n\u00eb sip\u00ebrfaqen e qelizave, duke provuar se proteina MAL \u00ebsht\u00eb \u00e7el\u00ebsi biologjik i k\u00ebtij sistemi t\u00eb ri t\u00eb grupeve t\u00eb gjakut.<\/strong><\/p>\n Ky zbulim jo vet\u00ebm q\u00eb zgjidh nj\u00eb enigm\u00eb 50-vje\u00e7are, por hap rrug\u00ebn p\u00ebr transfuzione m\u00eb t\u00eb sigurta dhe p\u00ebr diagnostikim m\u00eb t\u00eb sakt\u00eb t\u00eb rasteve t\u00eb rralla n\u00eb mjek\u00ebsin\u00eb moderne.<\/p>\n PIRUSTI NEWS<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":" Shkenc\u00ebtar\u00ebt kan\u00eb arritur t\u00eb zgjidhin nj\u00eb mister q\u00eb kishte mbetur i pazbardhur p\u00ebr m\u00eb shum\u00eb…<\/p>\n","protected":false},"author":2,"featured_media":19991,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"gallery","meta":{"footnotes":""},"categories":[701,709],"tags":[],"class_list":["post-19990","post","type-post","status-publish","format-gallery","has-post-thumbnail","hentry","category-aktualiteti","category-kryesor","post_format-post-format-gallery"],"yoast_head":"\n
\nKur k\u00ebto antigjene nuk p\u00ebrputhen gjat\u00eb nj\u00eb transfuzioni, mund t\u00eb ndodhin reagime serioze, madje edhe k\u00ebrc\u00ebnuese p\u00ebr jet\u00ebn.<\/p>\n